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KMID : 0191120220370200140
Journal of Korean Medical Science
2022 Volume.37 No. 20 p.140 ~ p.140
Croup as a Manifestation of SARS-CoV-2 Omicron Variant Infection in Young Children
Choi Youn-Young

Kim You-Sun
Lee Seong-Yong
Sim Ji-Woo
Choe Young-June
Han Mi-Seon
Abstract
Croup is an acute upper respiratory disease primarily caused by the parainfluenza virus. Owing to inflammation and edema of the upper airways, children present with barky cough and stridor, and some may experience respiratory distress. We investigated children aged < 5 years with coronavirus disease 2019 (COVID-19) admitted to two hospitals in Seoul, South Korea, and observed a spike in croup cases during the omicron surge. Among the 569 children admitted from March 1, 2021 to February 25, 2022, 21 children (3.7%) had croup, and the proportion of croup cases was significantly higher during the omicron wave than that during the delta wave (12.4% vs. 1.2%, P < 0.001). With the immediate administration of corticosteroids and epinephrine via nebulizer, the symptoms improved rapidly. During the current omicron surge, careful monitoring of the symptoms of croup in young children is needed for the diagnosis of COVID-19 and its timely management.
KEYWORD
Croup, Children, SARS-CoV-2, COVID-19, Omicron
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